#COLLAGEN BURN SKIN#

**-Pearson Chi-Square test Figures in parenthesis are in percentage The results were analyzed using вЂMann-Whitney testвЂ™ and вЂPearson Chi-Square testвЂ™ depending on the type of data.

#COLLAGEN BURN SKIN#

Response to the treatment and patientsвЂ™ outcome were noted in terms of progression of wound healing, granulation tissue formation, changes in edges of wounds and need of skin grafts. Both the groups were treated with antibiotics based on the pus culture sensitivity report. Wounds of the patients in the вЂConventional groupвЂ™ were dressed with povidone iodine, honey, nadifloxacin, or silver sulfadiazine etc. Dressing was then dried with a warm-air dryer. The movement of the forceps should be just similar to the movement of a knife while applying butter on a toast. This can be facilitated by using the back of the thumb-forceps to apply a little pressure from one end of the dressing to the other. Care should be taken to remove any air bubbles. Sheets were applied firmly so as to cover the whole raw area of wound/ulcer. Collagen sheets were rinsed in normal saline before application. Then, one or more collagen sheets (manufactured from intestine of cattle by The Central Leather Research Institute, Adyar, Chennai) of appropriate size are selected. Wound swab or pus culture was done every three to five days or when specifically required (hospital protocol).Д«efore applying collagen dressing, the affected area was thoroughly cleaned for removal of external contamination, and infected wound was debrided properly. The recorded data from the patientsвЂ™ files regarding characteristics of all wounds as size, edge, floor characteristics, slough, granulation tissue, pathogenic organisms and wound swab or pus culture sensitivity results were noted and analyzed. For the sake of analysis the patients were divided into two groups вЂCollagen groupвЂ™ and вЂConventional groupвЂ™. The patients with co-morbidities that could grossly affect the wound healing like uncontrolled diabetes mellitus, chronic liver or renal disease, other collagen disease or major nutritional deprivation were excluded.

We retrospectively collected the records of the patients with chronic wounds on different parts of the body and of various aetiologies, treated in our department with either collagen dressings or one of the conventional dressing materials/honey, over a period of four years (2006-2009). With start of treatment, appearance of granulation tissue, completeness of healing, need for skin grafting, and patientsвЂ™ satisfaction was noted for each patient in both groups. For assessment the wound characteristics (size, edge, floor, slough, granulation tissue, and wound swab or pus culture sensitivity results) were recorded. For the purpose of comparison the patients were divided into two groups вЂCollagen groupвЂ™ and вЂConventional groupвЂ™, each having 60 patients. Patients with co-morbidities that could grossly affect the wound healing like uncontrolled diabetes mellitus, chronic liver or renal disease, or major nutritional deprivation were not included. The patients had been treated either with collagen or other conventional dressing materials including silver sulfadiazine, nadifloxacin, povidone iodine, or honey (traditional dressing material). The records of 120 patients with chronic wounds of varied aetiologies and with mean age 43.7 years were collected and analyzed.

Collagen burn